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Once, she was just a harmless eColi bacteria named Bacter. Her tribe was peaceful, seeking only a home in which to grow and strive—and thought they’d found paradise upon first entering the BioCosmic Universe through a cut in Alex’s hand. When the Macrophages wiped them out, Bacter barely escaped—and was found by Raze, who used Conjugation to mutate her into something far more menacing to the health of the BioCosmos. Now, she’s bigger, stronger, and can use her spiked talons and poisonous spikes to tear apart BioWarriors. She has a special hatred for Scathe.

The Combine

A high tech cabal whose goal is to destroy and then rebuild human civilization around the principle of Survival of the Fittest. They’ve infiltrated the highest levels of government, business and law enforcement, and recruit only the most talented and driven individuals to join their ranks. In the way the Black Plague eventually gave rise to the Renaissance, The Combine envisions their Z-Kron Virus giving rise to a second Great Renaissance.


The Immune System’s “Intelligence Agents,” coordinating its response to pathogenic invasions by analyzing information received from the Council of the Mind, and using it to effectively deploy BioWarriors such as B-Cells, Macrophages, and Natural Killer Cells. They are based in satellite Lymph Nodes located throughout the BioCosmos.

Taser Gun

An advanced handheld electronic weapon carried by The Combine Agents. Its charge can be adjusted to induce a full range of effects on Combine prey—from stunning to paralysis to termination.

Thalamic Chamber

The mythical, cathedral like space nestled between the twin hemispheres of the brain. Here, the supreme neuron cells known as The Council of the Mind receive and interpret thoughts, impulses, and emotions emitted by a brilliant corona of energy high above. In turn, they transmit this information throughout the BioCosmos by way of messenger nerve cells.

The Beyond

An enigmatic realm of unknown vastness that exists outside the barriers of the BioCosmos. It is the source of every invasive threat, every infection, every strain of bacteria—and as such, it is spoken of in hushed, sometimes fearful tones by BioWarriors. What they don’t know is that The Beyond is filled with billions of other human beings, each of whom holds within a separate Biocosmic universe.

The Eternal Dark

The end of all life in the BioCosmos, the time when all biods dim forever and the lifecore ceases to beat. Every BioWarrior knows instinctively that this event is inevitable, and yet they struggle against its passage ever second of their existence.

Thoracic Region

Also known as the chest, the Thoracic Region is a complex system of sweeping plains and caverns that house the thundering Life Core of the BioCosmos. It is in this sector that the BioWarriors first battle Raze’s and his minions, who inflicts massive damage before escaping.


A collection of identical cells in function and form, that together comprise a larger whole. Tissue is one of the main structures of the BioCosmos, giving it mobile ability and more. When this tissue is infected or damaged during the Biowars, it is mended by Fibroblasts.

The Major

The enigmatic and ruthless head of security for The Combine’s New York City headquarters. Her real name remains a mystery, but her skills as a hand-to-hand combatant, strategist, and taskmaster are legendary. After she targets Marcus Hawking for death, she soon finds herself hunting his son, Alex—and the chase is on.


A Monocyte, or junior member of the Macrophage Corps, who worships Scathe and desperately wants to match his mentor’s contagion-killing ways. Though not yet fully matured, he possesses the Macrophage traits of grasping tentacles, the ability to fire chemical heat blasts, and an abdominal cavity that disintegrates defeated foes with corrosive enzymes.